Youmu Konpaku (魂魄 妖夢 Konpaku Youmu) is a half-human half-phantom who lives at Hakugyokurou in the Netherworld as a gardener. She first appeared as the Stage 5 boss of Perfect Cherry Blossom, the seventh installment of the Touhou Project.
Sanae Kochiya (東風谷 早苗 Kochiya Sanae) is a human, but is also a distant descendant of the goddess Suwako Moriya. Her role at the Moriya Shrine is similar to a shrine maiden. She is also from the Touhou Project.
Reimu Hakurei (博麗 霊夢 Hakurei Reimu) is the main protagonist of the Touhou Project series along with the deuteragonist, Marisa Kirisame. As the shrine maiden of the Hakurei Shrine, she manages the Hakurei Border of Gensokyo.
Marisa Kirisame (霧雨 魔理沙 Kirisame Marisa) is an ordinary human magician who specializes in light and heat magic and currently resides in the Forest of Magic. She is considered to be the deuteragonist of the Touhou Project series.
Sakuya Izayoi (十六夜 咲夜 Izayoi Sakuya) is the Chief Maid who serves Remilia Scarlet, the head of the Scarlet Devil Mansion. She is the only human living in the Scarlet Devil Mansion. She is also from the Touhou Project.
Clownpiece (クラウンピース Kuraunpīsu) is a fairy of Hell. Like many of the other fairies in Touhou: she is playful, mischievous, childish, and a little bit dumb. She currently lives under the Hakurei Shrine in a replica Hell she made for herself.
Seija Kijin (鬼人 正邪 Kijin Seija) is the main protagonist of Impossible Spell Card and the minigame Gold Rush. She's an amanojaku with the power to turn over anything. She resides in the Shining Needle Castle. She is also from the Touhou Project.
Reisen Udongein Inaba (鈴仙・優曇華院・イナバ) is one of the moon rabbits who fled from the Moon to Earth as a refugee from the "Lunar War" between the two worlds that began in 1969 A.D. after the Apollo 11 "invasion". She is also from the Touhou Project.