The Ultimate Vanilla+ Modpack!

NOTEWORTHY GAME-ALTERING MODS

TeammateRevival (Allows you to revive teammates, at a cost. Highly configurable and vanilla friendly)
Exchange_Changes (Speed up interactable speed)
ReduceRecycler (Recycler has no cooldown but the cooldown is added to the run timer. Can be configured)
FasterInteracableBalancer (Adds a second to the timer when using faster interactables)
NoAllyAttackBlock (Hit through allies)
EliteWorms (Magma Worms and Overloading Worms can gain elite aspects)
LittleGameplayTweaks (https://thunderstore.io/package/Wolfo/LittleGameplayTweaks/)
PressureDrop (Pressure plates stay pressed for a duration. No need for pot rolling!)
DoshDrop (Drop money)
BadassEmotes (Fun but does detract from Vanilla)

VanillaVoid (Adds void items for some vanilla items that didn't get that special love)
StarStorm2 (Adds items, events, survivors and more. Highly configurable)
Cloudburst (Adds items, survivors and more. Highly configurable)
FreeItemFriday (Adds items and skills)

ProceduralStages (Every stage is different! Has a chance to break in multiplayer, with other map mods or aesthetic mods)
StageAesthetic or CoolerStages (Stages feel a bit more unique with these. Incompatible with each other and ProceduralStages)
RobItems (Rob Items)
Ephemeral Coins (Don't like how easy lunar coins make the game? Now they only persist per stage!)
TinkersSatchel (More items, more skills, more artifacts)
All of HIFU's mods (Lots of tweaks and new ways to experience RoR2)
All of Moffeins mods (Tons of fun changes to the base game and more)
All of Nuxlars mods (More fun changes to the base game and more)
FogboundLagoon (An additional map that feels like vanilla)